Yslow and Google Page Speed insights are useful for measuring the client side performance but i think they are not suitable for speed analysis and comparisons(you can compare the progress in your ui performance according to the suggested enhancements)
Webpagetest.org is useful as well because you can select the region and the browser and you can record video as well but it only available for published websites so it cannot be used during development or enhancing a local website.
Network tab in Google Chrome is very useful for getting page load time and it can be done to get a quick info without the need to start a performance project in a PT tool.
